Guidebook
UCLA Antibiotic Handbook
2011-2012
Introduction
How to use this guide
Important Phone Numbers
Microbiology Overview
Interpretations of Key Phrases
Bacteriology
Macro Micro Misconceptions
Bacteriuria in Patients with Neurogenic Bladder and/or Indwelling Catheters
VRE in the Stool (VRE Colonization)
The role of Candida isolated from bronchoscopic samples in non-neutropenic patients
"Double coverage"
Anaerobes
Antimicrobial Formulary and Restriction Status
Restricted antimicrobials
Antimicrobial Fundamental Concepts
Pharmacodynamics and Therapeutic Drug Monitoring
“Double coverage”
Gram-negative Bacteria
Anaerobes
Laboratory and Clinical Toxicity Monitoring
Antibiotic Overview
Ampicillin/sulbactam (Unasyn)
Colistin (Colistimethate)
Daptomycin
Ertapenem
Linezolid
Tigecycline
Vancomycin
Acceptable empiric use
Acceptable use of definitive intravenous therapy
Acceptable use for definitive oral therapy
Acceptable use for prophylaxis
Unacceptable uses for vancomycin
Dosing
Antifungals
Caspofungin
Aspergillosis
Candidiasis
Neutropenic Fever
Posaconazole
Voriconazole
Infectious Syndromes
Specific Treatment of Select Bacterial Organisms at UCLA
Clostridium Difficile
Central Nervous System Infections
Bloodstream Infections
Central line-associated bloodstream infection (CLABSI)
Coagulase-negative staphylococci (CoNS)
Staphylococcus aureus
Enterococcus faecalis
Enterococcus faecium
Gram-negative bacilli
Pulmonary Infections
Community-acquired pneumonia in hospitalized patients
Healthcare-associated Pneumonia (NOT ventilator-associated)
Ventilator-associated Pneumonia (VAP)
Seasonal Influenza Diagnosis and Management
Tuberculosis (TB) Infection
Sepsis
Skin and Soft Tissue Infections
Cellulitis
Cutaneous Abscess
Recurrent MRSA Skin Infections
Diabetic Foot Infections
Surgical Site Infections (SSI)
Necrotizing Fasciitis
Urinary Tract Infections
Non-catheter-associated UTI
Catheter-associated UTI (CAUTI)
Abdominal Infections
Biliary Tract Infections
Pancreatitis
Peritonitis
Resistant Gram Negative Infections
Candidiasis in non-neutropenic patients
Oropharyngeal disease (Thrush)
Esophageal Candidiasis
Candiduria
Vaginitis
Candidemia
Endophthalmitis
Endocarditis
Hematologic Malignancies
Cytomegalovirus Infection and Disease
Fever and Neutropenia
Fungal Disease
Interstitial Pneumonia
Other Viral Infections in Immunocompromised Hosts
Surgical Prophylaxis
Endocarditis Prophylaxis
Penicillin Allergy
Prophylactic Antimicrobials for Patients with Solid Organ Transplants
Antimicrobial Therapy in Head and Neck Surgery
Acknowledgments
UCLA Internal Links
